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| Year | Date | Colliery | Company | Location of Colliery | Cause of Accident | Number Killed |
| 1847 | Feb. | Spencer | Spencer Coal Co. | Pottsville | Explosion of gas | 7 |
| 1869 | Sep. 6 | Avondale | Delaware, Lackawanna & Western Railroad Co. | Plymouth | Mine fire | 110 |
| 1870 | Mar. 22 | Potts | Locust Dale Coal Co. | Locust Dale | Boiler explosion | 5 |
| Aug. 10 | Heins & Glassmire | Heins & Glassmire | Middleport | Cage fell down shaft | 9 | |
| Aug. 29 | Preston No. 3 | Preston Coal & Improvement Co. | Girardville | Car fell down slope | 7 | |
| 1871 | May 27 | West Pittston | Lehigh Valley Railroad Co. | West Pittston | Suffocated by smoke from burning breaker | 20 |
| Oct. 2 | Otto Red Ash | Cain, Hacker & Cook | Branch Dale | Explosion of gas | 5 | |
| 1873 | June 10 | Henry Clay | Langdon & Co., R. | Shamokin | Explosion of gas | 10 |
| 1877 | May 9 | Wadesville | Wadesville Shaft Colliery | Wadesville | Explosion of gas | 7 |
| 1878 | Jan. 15 | Potts | Philadelphia & Reading Coal & Iron Co. | Locust Dale | Explosion of gas | 5 |
| 1879 | May 6 | Audenried | Lehigh & Wilkes-Barre Coal Co. | Audenried | Explosion of gas | 6 |
| No. 2 | Mill Creek | D. & H. Canal Co. | Mill Creek | Explosion of Gas | 5 | |
| 1880 | May 3 | Lykens Valley | Short Mountain & Lehigh Valley Coal Co. | Shamokin | Explosion of gas | 5 |
| 1882 | May 24 | Kohinoor | Heckscher & Co., R. | Shenandoah | Explosion of gas | 5 |
| 1884 | Aug. 21 | Buck Ridge | Philadelphia & Reading Coal & Iron Co. | Shamokin | Mine fire | 7 |
| 1885 | Apr. 6 | Cuyler | Heaton & Co., S. M. | Raven Run | Fall of Roof | 10 |
| Aug. 11 | West End | West End Coal Co. | Mocanaqua | Suffocated by gas from boiler fire | 10 | |
| Oct. 21 | Plymouth No. 2 | D. & H. Coal Co. | Plymouth | Explosion of gas | 6 | |
| Dec. 18 | Nanticoke No. 1 | Susquehanna Coal Co. | Nanticoke | Inrush of quicksand | 26 | |
| 1886 | Aug. 30 | Fair Lawn | Fair Lawn Coal Co. | Scranton | Explosion of gas | 6 |
| Sep. 13 | Marvine | D. & H. Coal Co. | Scranton | Suffocated by gas | 8 | |
| Nov. 26 | Conyngham | D. & H. Coal Co. | Wilkes-Barre | Explosion of gas | 12 | |
| 1887 | Apr. 27 | Tunnel | Philadelphia & Reading Coal & Iron Co. | Ashland | Suffocated by gas | 5 |
| Oct. 1 | Bast | Philadelphia & Reading Coal & Iron Co. | Big Mine Run | Explosion of gas | 5 | |
| 1890 | Feb. 1 | Nottingham | Lehigh & Wilkes-Barre Coal Co. | Plymouth | Explosion of gas | 8 |
| Mar. 3 | S. Wilkes-Barre No. 3 | Lehigh & Wilkes-Barre Coal Co. | Wilkes-Barre | Explosion of gas | 8 | |
| Apr. 2 | Susquehanna No. 4 | Susquehanna Coal Co. | Nanticoke | Explosion of gas | 5 | |
| May 15 | Jersey No. 8 | Lehigh & Wilkes-Barre Coal Co. | Ashley | Explosion of gas | 26 | |
| 1891 | Feb. 4 | Spring Mountain No. 1 | Spring Mountain Coal Co. | Jeanesville | Drowned-water from old workings | 13 |
| Oct. 23 | Richardson | Philadelphia & Reading Coal & Iron Co. | Glen Carbon | Suffocated by gas | 7 | |
| Nov. 8 | Susquehanna No. 1 | Susquehanna Coal Co. | Nanticoke | Explosion of gas | 12 | |
| 1892 | Apr. 20 | Lytle | Lytle Coal Co. | Minersville | Drowned-water from old workings | 10 |
| July 23 | York Farm | Lehigh Valley Coal Co. | Pottsville | Explosion of gas | 15 | |
| 1893 | Apr. 1 | Neilson | Langdon & Co., Inc., A. L. | Shamokin | Mine fire | 10 |
| July 22 | Susquehanna No. 1 | Susquehanna Coal Co. | Nanticoke | Explosion of gas | 5 | |
| Sep. 21 | Lance No. 11 | Lehigh & Wilkes-Barre Coal Co. | Plymouth | Explosion of gas | 6 | |
| 1894 | Feb. 13 | Gaylord | Kingston Coal Co. | Plymouth | Fall of roof | 13 |
| July 17 | East Sugar Loaf | Linderman & Skeer | Stockton | Explosion of powder & dynamite | 8 | |
| Oct. 8 | Luke Fidler | Mineral Railroad & Mining Co. | Shamokin | Mine fire | 5 | |
| Oct. 11 | Henry Clay | Philadelphia & Reading Coal & Iron Co. | Shamokin | Boiler explosion | 6 | |
| 1895 | Feb. 18 | West Bear Ridge | Philadelphia & Reading Coal & Iron Co. | Mahanoy Plane | Explosion of gas | 5 |
| Oct. 7 | Dorrance | Lehigh Valley Coal Co. | Wilkes-Barre | Explosion of gas | 7 | |
| 1896 | June 28 | Twin | Newton Coal Co. | Pittston | Fall of roof | 58 |
| Oct. 29 | S. Wilkes-Barre No. 3 | Lehigh & Wilkes-Barre Coal Co. | Wilkes-Barre | Explosion of gas | 6 | |
| 1897 | Jan. 13 | Wadesville | Philadelphia & Reading Coal & Iron Co. | Wadesville | Crosshead fell down shaft | 5 |
| Sep. 28 | Jermyn No. 1 | Jermyn & Co. | Rendham | Mine fire | 5 | |
| Oct. 30 | Von Storch | D. & H. Coal Co. | Scranton | Mine fire | 6 | |
| 1898 | May 26 | Kaska, William | Dodson Coal Co. | Middleport | Drowned-water from old workings | 6 |
| May 26 | Kaska, William | Dodson Coal Co. | Middleport | Drowned-water from old workings | 6 | |
| Oct. 1 | Midvale | Lehigh Valley Coal Co. | Wilkes-Barre | Mine fire | 6 | |
| Nov. 5 | Exeter | Lehigh Valley Coal Co. | West Pittston | Car fell on cage in shaft | 9 | |
| 1900 | Nov. 9 | Buck Mountain | Mill Creek Coal Co. | Mahanoy City | Explosion of gas | 7 |
| 1901 | Oct. 25 | Buttonwood | Parrish CoalCo. | Plymouth | Explosion of gas | 6 |
| 1902 | Nov. 29 | Luke Fidler | Mineral Railroad & Mining Co. | Shamokin | Explosion of gas | 7 |
| Dec. 9 | S. Wilkes-Barre | Lehigh & Wilkes-Barre Coal Co. | Wilkes-Barre | Explosion of powder & dynamite | 5 | |
| 1904 | Jan. 30 | Maple Hill | Philadelphia & Reading Coal & Iron Co. | Mahanoy City | Explosion of powder & dynamite | 5 |
| May 5 | Lance | Lehigh & Wilkes-Barre Coal Co. | Plymouth | Explosion of powder & dynamite | 5 | |
| May 5 | Locust Gap | Philadelphia & Reading Coal & Iron Co. | Locust Gap | Mine fire | 5 | |
| May 25 | Williamstown | Summit Branch Mining Co. | Williamstown | Suffocated by gas from mine locomotive | 10 | |
| Nov. 2 | Auchlincloss | Delaware, Lackawanna & Western Railroad Co. | Nanticoke | Falling down shaft | 10 | |
| 1905 | Feb. 18 | Lytle | Lytle Coal Co. | Minersville | Fall of roof | 5 |
| Mar. 9 | Clear Spring | Clear Spring Coal Co. | West Pittstown | Falling down shaft | 7 | |
| Apr. 26 | Conyngham | D. & H. Coal Co. | Wilkes-Barre | Falling down shaft | 10 | |
| 1906 | May 15 | Shenandoah City | Philadelphia & Reading Coal & Iron Co. | Shenandoah | Explosion of powder & dynamite | 7 |
| Aug. 6 | Susquehanna No. 7 | Susquehanna Collieries Co. | Nanticoke | Explosion of gas | 6 | |
| 1907 | Mar. 2 | Holden | Delaware, Lackawanna & Western Railroad Co. | Taylor | Explosion of gas | 7 |
| 1908 | June 18 | Johnson No. 1 | Scranton Coal Co. | Priceburg | Explosion of gas | 7 |
| May 12 | Mount Lookout | Temple Iron Co. | Wyoming | Explosion of gas | 12 | |
| May 13 | Prospect | Lehigh Valley Coal Co. | Midvale | Fall of roof | 5 | |
| July 15 | Williamstown | Summit Branch Mining Co. | Williamstown | Explosion of powder & dynamite | 6 | |
| Aug. 28 | Warrior Run | Lehigh Valley Coal Co. | Wilkes-Barre | Mine cars | 6 | |
| 1909 | Mar. 2 | Pennsylvania No. 14 | Pennsylvania Coal Co. | Pittston | Explosion of gas | 8 |
| Nov. 9 | Auchlincloss | Glen Alden Coal Co. | Nanticoke | Mine fire | 9 | |
| 1910 | Jan. 11 | Nottingham | Lehigh & Wilkes-Barre Coal Co. | Plymouth | Explosion of gas | 7 |
| Mar. 12 | S. Wilkes-Barre No. 5 | Lehigh & Wilkes-Barre Coal Co. | Wilkes-Barre | Explosion of gas | 7 | |
| 1911 | Apr. 7 | Pancoast | Price-Pancoast Coal Co. | Throop | Mine fire | 72 |
| May 10 | Plymouth No. 5 | Delaware & Hudson Co. | Dorrancetown | Suffocated by gas from underground fire | 5 | |
| May 27 | Cameron | Mineral Railroad & Mining Co. | Shamokin | Explosion of gas | 5 | |
| Sep. 12 | Marvine | Delaware & Hudson Co. | Scranton | Mine cars | 5 | |
| Oct. 3 | Drifton No. 2 | Coxe Bros. Co., Inc. | Freeland | Cave-in | 5 | |
| 1912 | Jan. 9 | Parrish | Parrish Coal Co. | Plymouth | Explosion of gas | 6 |
| 1913 | Aug. 2 | East Brookside | Philadelphia & Reading Coal & Iron Co. | Tower City | Explosion of gas | 20 |
| 1914 | May 29 | Maryd | Maryd Coal Co. | Maryd | Overwinding of cage | 6 |
| Sep. 16 | Lehigh No. 4 | Lehigh Coal & Navigation Co. | Lansford | Explosion of gas | 7 | |
| Dec. 9 | Diamond | Delaware, Lackawanna & Western Railroad Co. | Scranton | Falling down shaft | 13 | |
| 1915 | Feb. 17 | Prospect | Lehigh Valley Coal Co. | Wilkes-Barre | Explosion of gas | 13 |
| 1916 | Feb. 8 | Lance No. 11 | Lehigh & Wilkes-Barre Coal Co. | Plymouth | Explosion of gas | 7 |
| Mar. 9 | Hollenback No. 2 | Lehigh & Wilkes-Barre Coal Co. | Wilkes-Barre | Explosion of gas | 6 | |
| Aug. 8 | Woodward | Delaware, Lackawanna & Western Railroad Co. | Edwardsville | Explosion of gas | 6 | |
| 1919 | June 5 | Baltimore Tunnel | Hudson Coal Co. | Wilkes-Barre | Explosion of powder & dynamite | 92 |
| July 8 | Lansford | Lehigh Coal & Navigation Co. | Lansford | Explosion of gas | 8 | |
| 1921 | Mar. 9 | Rahn | Lehigh Coal & Navigation Co. | Seek | Explosion of gas | 5 |
| 1922 | Nov. 3 | Eddy Creek | Hudson Coal Co. | Scranton | Premature blast | 6 |
| 1923 | Feb. 21 | Alliance | Alliance Coal Mining Co. | Middleport | Explosion of gas | 5 |
| June 26 | Richards | Susquehanna Collieries Co. | Mount Carmel | Explosion of gas | 5 | |
| Dec. 8 | Mount Jessup No. 2 | Mount Jessup Coal Co. | Jessup | Fall of roof | 5 | |
| 1924 | June 6 | Loomis | Glen Alden Coal Co. | Nanticoke | Explosion of gas | 14 |
| 1925 | May 22 | Woodward | Glen Alden Coal Co. | Edwardsville | Explosion of gas | 7 |
| Aug. 3 | Dorrance | Lehigh Valley Coal Co. | Wilkes-Barre | Explosion of gas | 10 | |
| 1926 | May 6 | Randolph | So. Penn Collieries Co. | Port Carbon | Explosion of gas | 5 |
| July 3 | Pettebone | Glen Alden Coal Co. | Kingston | Explosion of gas | 7 | |
| Oct. 30 | Susquehanna No. 7 | Susquehanna Collieries Co. | Nanticoke | Explosion of gas | 9 | |
| 1927 | May 26 | Woodward | Glen Alden Coal Co. | Edwardsville | Fall of roof, followed by an explosion of gas | 7 |
| 1928 | May 25 | Baltimore No. 5 | Hudson Coal Co. | Wilkes-Barre | Explosion of gas | 10 |
| 1930 | Aug. 8 | Gilberton | Philadelphia & Reading Coal & Iron Co. | Gilberton | Fall of roof | 8 |
| 1931 | May 29 | Richards | Susquehanna Collieries Co. | Mount Carmel | Explosion of gas | 5 |
| 1935 | Jan. 21 | Gilberton | Philadelphia & Reading Coal & Iron Co. | Gilberton | Explosion of gas | 13 |
| May 7 | S. Wilkes-Barre | Glen Alden Coal Co. | Wilkes-Barre | Piece of rock fell down shaft, struck cage | 7 | |
| 1936 | Aug. 24 | Clear Spring | Sullivan Trail Coal Co. | West Pittston | Explosion of gas | 5 |
| 1938 | Apr. 27 | St. Clair | St. Clair Coal Co. | St. Clair | Explosion of gas | 8 |
| June 2 | Volpe | Volpe MiningCo. | Pittston Twp. | Explosion of gas | 10 | |
| 1943 | Sep. 24 | Primrose | M. & S. Coal Co. | Minersville | Explosion of gas | 14 |
| 1947 | Jan. 15 | Nottingham | Glen Alden Coal Co. | Wilkes-Barre | Explosion of gas | 15 |
| Apr. 10 | Schooley | Knox Coal Co. | Exeter Boro. | Explosion of gas | 10 | |
| Dec. 11 | Franklin | Lehigh Valley Coal Co. | Wilkes-Barre | Explosion of gas | 8 | |
| 1951 | Mar. 29 | Buttonwood | Glen Alden Coal Co. | Hanover Twp. | Explosion of gas | 5 |
| 1952 | Mar. 27 | Holmes Slope | Cano & Martin, Inc. | Forrestville | Drown-blast blew through to old workings | 5 |
| 1959 | Jan. 22 | Ewen | Knox Coal Co. | Port Griffith | Drown - river broke into mine | 12 |
| 1977 | Mar. 1 | Porter Tunnel | Kocher Coal Co. | Tower City | Inrush of water | 9 |
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